Ibutamoren (MK-677) is a kind of SARM and an effective growth hormone secretagogue that mimics the effects of GH stimulation against ghrelin-endogenic hormone. Over the past decade has been studied to treat the IGF-1 deficiency rate and low growth in older children and adults. Interestingly, nutrition is safer and cheaper than growth hormone. Today, athletes have started using these effective compounds as enhancers to increase endurance, lose weight and increase muscle mass.
How does ibutamoren, mk 677 work? The intensity of the pulse growth hormone can be increased through four possible mechanisms and they are as follows:
– Increases the release of GHRH hormone (growth hormone release hormone).
– Strengthens the GHRH signal in somatotroph in the anterior pituitary gland.
– Reduces somatostatin release (somatostatin kills GH release).
– Inhibits somatostatin receptor signals.
Ibutamoren (MK-677) is found to work through these four mechanisms. After consumption, Growth Hormone (GH) is shown to increase the dose depending on the starting dose of five milligrams (mgs) per day.